There is now a product which contains all 8 essential sugars called Now Glyconutrient Complex. It is good for those who don't want to bother with the recipes below, although something like glyconutrient pudding along with kelp capsules will provide more glyconutrients for the money.
Reprinted from http://www.burnoutsolutions.com.au/glyconutrients.htm
Glyconutrient Jam and Glyconutrient Powder Recipe: An Inexpensive Way of
Getting "Essential" sugars
Last modified 21 Sept 2005
Disclaimer: These notes are not to be
construed as personal medical advice. Consult your qualified health
professional. No information on this web site is to be seen as a treatment for
any specific illness. I do not endorse the use of this recipe as a substitute
for proven therapy or for a doctor's care or for the treatment of any specific
illness. This information is simply
presenting a recipe that I have personally used, am aiming to use, or am
considering using. I am interested in it personally as a source of normal food
nutrients for the maintenance of optimal health. This material is simply shared
for what its worth in the hope of saving others time and or money as they do
research. This material is not copyrighted, but this disclaimer should be added
if it is copied. It should not be sold or otherwise used to make a profit.
I am not in a position to answer questions about this page
due to time constraints. Suggestions on improving this page are welcome
however. Email firstname.lastname@example.org. I have
received a number of testimonials concerning improvements in well-being as a
result of this recipe but due to time constraint I have decided not to publish
This site has been prepared by Dr David Bird MBChB, Dip Obst.,
Dip Clinical Nutrition, FACNEM.
Please note that I not think that a "magic bullet" approach to
health is a good idea. Any health food recipe should be seen as helping to
promote optimum health IN THE CONTEXT of a healthy overall lifestyle. A "healthy
overall lifestyle" would, in my opinion, include (but is not limited to):
- Avoiding high fat, high sugar "junk food" diets. Enjoying sufficient exercise. Enjoying drinking plenty of pure water. Getting adequate sunshine and fresh air. Avoiding environmental poisons and other "personal" poisons such as
nicotine and alcohol. Getting priorities in a healthy order so as to avoid undue stress. Trusting in God.
- Getting adequate sleep and rest.
For more suggestions please see TIPS ON HEALTH AND
The eight "essential"1 sugars are: mannose, glucose, galactose, xylose, N-acetylglucosamine, N-acetylgalactosamine,
fucose (not to be confused with fructose), and N-acetylneuraminic acid. They are
very important for health. I will not spend time dwelling on all the benefits as
others have already done this in amble detail. In addition to the essential
sugars, most of the ingredients in this recipe provide other health promoting
properties as well. The aim here is to provide a simple and inexpensive way of
getting glyconutrients. So let us now look at these eight sugars and see where
we can get them from .
1. Mannose. Mannose may be the single most important of
the eight sugars for us to get plenty of. One of the main sources is aloe vera,
which contains acemannan. Acemannan is a mannose polysaccharide (i.e. a chain of
mannose molecules). From what I’ve studied, most commercial supplements of aloe
only have very small amounts of acemannan in them so the best way is to grow the
aloe vera oneself. It is a very handy herb to have in the garden or green house
(e.g. good for minor burns and some skin ailments) and it is easy to cultivate.
Consult a gardening book, but apparently it needs a sunny spot that’s not too
moist. I may want to enjoy using plenty of it, so ideally would like to invest
in about ten plants. While I are waiting to buy and establish my own aloe plants
I can use the glyconutrient powder which does have mannose in as well. This is
from the kelp, the shiitake and the ground fenugreek. I have actually
recently decided to just take the glyconutrient powder (as detailed below)
because I find it easier. There are also concerns about diarrhoea, etc. from the
skin of the leaves. Fenugreek contains plenty of galactomamman, a
polysaccharide of mannose and galactose (other sources of galactomamman are
carob gum and guar gum). Ground fenugreek should be readily available from a
good health food store or supermarket, or I can buy the seeds and grind them
myself. I prefer organic fenugreek. Shiitake mushrooms have in them a compound
called KS-2 which contains mannose bound to an amino acid. We will say more
about shiitake (and kelp) later. Using fenugreek, kelp and shiitake should not
be very expensive. Aloe vera plants may be expensive to start with, but a friend
may have a "jungle" of the plants and be able to give some.
2. Glucose. Regarding the powder, glucose is found in
kelp. But we don't really need to supplement glucose as its so abundant in our
diets anyway. For the "jam" recipe the prime source is 100% pure grape juice,
preferably dark organic (but I don’t worry if its not feasible). The grape juice
will help, along with the next item, to make the aloe vera taste yummy instead
of yuck. This juice is relatively cheap and if I have a juicer I can make my
3. Galactose. Galactose is present in the fenugreek of
the powder and also in a lot of foods that we normally eat. For the "jam" recipe
the prime source is 100% pure apple juice, preferably organic. This juice will
help, along with the previous item, to make the aloe vera taste yummy. Both
apple and grape juice have health properties of their own. Again this juice is
relatively cheap and those with juicers can make their own. Some analyses don’t
report galactose as being in Apple juice. This is because the galactose is in
the pectin fibre which is present in varying amounts in juice.
4. Xylose. Xylose is present in the kelp used in the
powder. Ground psyllium seeds are high in a xylose polysaccharide. They are
cheap and easily obtained from a chemist or health food store. Psyllium is used
in the "jam".
5 and 6. N-acetylglucosamine and N-acetyl-galactosamine.
Vegetable sources: For those not wishing to consume
medicinal animal products orally it is nice to know that Shiitake Mushroom
contains N-acetylglucosamine (as a constituent of chitin). I can purchase fresh
and/or dried Shiitake Mushrooms from many supermarkets and food stores. I buy
dried whole shiitake mushrooms and powder them by using my liquidiser. Or I can
buy a tablet with shiitake in. Shiitake Mushrooms do not contain N-acetyl-galactosamine.
I thought that mistletoe contained N-acetyl-galactosamine but it appears that it
does not. Instead it seems to contain a lectin that is specific for the
N-acetyl-galactosamine receptor site. Also there are some toxicity issues with
mistletoe. N-acetyl-galactosamine is contained in dextran sulphate, which is
present in a red algae called Dumontiaceae. But it appears that this product is
hard to get except in Japan.
Animal Sources: Bovine cartilage and shark cartilage
both have an abundance of these two essential sugars. These are both relatively
cheap and available from a chemist or health food stores in capsules or loose
powder. I prefer the bovine cartilage because it is predominantly the
chondroitin 4-Sulfate form of chondroitin which is apparently slightly better
(shark is predominantly chondroitin 6-Sulfate). I am not especially concerned
about prions and mad cow disease from a bovine source because I can check where
the cows come from and cartilage is not one of the tissues especially at risk
for prion contamination. Actually, from what I’ve read, chondroitin is a
substance that can be used to help treat prion disease as it interferes with the
prions doing their dirty work in the nervous tissue. I am more concerned about
the possibility of heavy metal contamination in shark cartilage, though I have
not read any major problems regarding this. Those not wishing to consume animal
products orally could use an arthritis cream containing chondroitin sulphate.
The best cream I know of is Arthro-Aid DirectÔ ,
which could be rubbed on the tummy at the time the glyconutrient powder is
7. Fucose. Kelp seaweed is rich in fucoidan, a
polysaccharide containing plenty of fucose. Fucoidin is a complicated molecule
that also contains xylose, mannose, galactose, and glucose. If anyone has an
overactive thyroid they should not take this or other sea weeds without medical
advice and monitoring. An complementary is beer yeast, which, according to my
research, also contains plenty of fucose. Kelp has many health benefits and can
be bought cheaply as a powder. It does not taste good to me!
8. N-acetylneuraminic acid (otherwise known as sialic
acid) is found in whey protein isolate. Whey protein isolate also contains lots
of other goodies. If allergic to diary (though I am told some that are allergic
to diary can take the isolate) an complementary is egg, which may be best raw. I
need to make sure it is an organic egg from a healthy chicken. I need to make
sure I buy whey protein ISOLATE, not just whey protein or whey powder. A 500g
pot of whey protein isolate is a little costly but will last a long time and so
is not a big expense long term. Note: I received some information early 2004
that suggested whey protein concentrate may have a higher amount of N-acetylneuraminic
acid in it they the isolate.
How I can prepare and consume the ingredients:
TWO items will be discussed:
1. A glyconutrient powder which provides all 8 essential
sugars at a minimal cost. The powder is more convenient to take and use than the
"jam" and I am not currently using the "jam" -- just concentrating on the
2. The glyconutrient jam which, if made correctly, tastes
yummy and which is designed to give large amounts of the key monosaccharide
1. Glyconutrient Powder
Here are the powders, the glyconutrients they contain and the
ratio for consumption (the ratio is by volume, not weight and is offered as a
guide only. When I make it up I don't measure out everying exactly):
- 1 part ground fenugreek: mannose, galactose (buy it already ground).1/4 part shiitake mushroom powder: N-acetylglucosamine, mannose.1 part kelp powder: fucose, xylose, mannose, galactose, and glucose.1 part whey protein isolate: N-acetylneuraminic acid. complementary is
beer or brewing yeast.1 part bovine or shark cartilage chondroitin sulphate powder (loose or
in capsules): N-acetylglucosamine, N-acetylgalactosamine). An complementary is Dumontiaceae (http://www.dynamune.com/#RMA) for
- 1/2 part of ground psyllium (I use the husks alone because otherwise I
have to grind husks myself. But purists may want to do the grinding) to
boost the xylose content as there is not that much xylose in kelp.
I am currently mixing all powders together. Sometimes I add a
little red cayenne pepper powder and a little turmeric powder too.
I believe cayenne enhances my digestion and is an extra tonic (1/10-1/20th
part). Turmeric has antioxidant properties.
I am also adding 1 part of lecithin granules as I have been
told that this very greatly enhances absorption of glyconutrients.
To make the powder taste nice I use a flavoured vitamin C
powder from GNLD. I am told that "Vita Fit" Vitamin C powder is good for this
purpose to. I think that about 2 parts by volume would do. I usually take the
mixture mixed with a juice. My children prefer soy milk.
complementaryly, I could take it with yogurt etc. or put the
powder into "OO" size vegetable capsules to consume. Ideally, I would take five
size "OO" capsules twice a day before meals. An complementary, if I wished to
avoid mixing powders, would be to take one "OO" capsule of each powder twice a
day before meals.
Maybe I could also take my powder mixed with an equal amount
of honey. Honey occasionally contains spores of Clostridium botulinum - the
Detrimental Bacteria that can cause the type of food poisoning called Botulism.
For this reason, honey should not be fed to children under 12 months old.
Whey protein isolate can be taken "sublingually" in small
amounts too. I am told that this is an even better way of taking it. But it can
take awhile to "dissolve".
Kelp and Wakame seaweeds (Asian style), shiitake, fenugreek
and whey isolate are all foods that can simply be eaten as part of a meal. There
should be a good way of having all these items at a meal say twice a week using
for example, wakame, fenugreek, shiitake, rice and vegetables with whey isolate
mixed with dates and soy yoghurt for dessert. We need some good chief to come up
with a tasty recipe for us to use! Have this meal with a chondroitin sulphate
capsule and you've got all 8 sugars!
2. Glyconutrient Jam
Slowly simmer (don’t boil) 1 litre grape juice and 1.5 litres
of apple juice so that half the water evaporates. Before turning off the heat
stir in about 1/4 cup of ground psyllium. IMPORTANT: MAKE SURE NOT TO PUT IN TOO
MUCH PSYLLIUM AS IT WILL TURN INTO A SOLID JELLY THAT IS NO GOOD FOR MIXING
THINGS WITH. I err on the side of too little psyllium then add more if needed.
Keep stirring for a couple of minutes or so then turn off the heat and let it
sit. It will turn into a kind of jelly that tastes like jam. The heat should
help to break down the psyllium polysaccharide into the xylose molecules. Store
in a jar in the fridge.
When I wish to take my glyconutrient jam I put 1/4-1/3 of a
cup of the grape, apple and psyllium jelly into a container. I grab about 4-5cm
of an average aloe vera leaf from my garden and using a pair of scissors or
knife chop it into the jam. Note: aloe contains a laxative so diarrhea is a sign
that I am taking too much. If you get diarrhea (from the yellow aloin just under
the skin) then try scraping out and eating just the gel. I stir the aloe bits in
and then eat it with a spoon. The aloe and jam should taste nice, but if not
happy I can try cutting the aloe vera into smaller pieces or liquidising it into
the jam. This further improves taste but ends up taking more time, especially to
clean up! The aloe vera needs consuming soon after picking and chopping as I am
told aloe vera’s mannose is quickly damaged or degraded after a leaf is picked.
The glyco-jam is easiest taken as a kind of entrée 10-30
minutes before meals or on its own as a supper in the evening. I would aim, for
maintenance, to take this mixture three times a week or daily. For nutritional
support when ill I could be take it more frequently.
Sources of Glyconutrients
The following is given due the paucity of information that
seems to be currently available. It comes mainly from the Hyperhealth CD ROM,
In-Tele-Health © 2003 and is for personal and educational purposes only. I
highly recommend the purchase of the Hyperhealth CD ROM that is available as
Australia:Hyperhealth, 20 Napier Street, Fitzroy, VIC 3065
Phone: (03) 9417-2567
Fax: (03) 9417-2567
USA: Hyperhealth, P.O. Box 37, Hansville, WA 98340
Phone: (360) 638-2898
Fax: (360) 638-2898
Dietary Sources of Mannose
Blackcurrants Currants - Red
Beans - Green
Dietary Sources of Xylose
Beans - Green
Dietary Sources of Glucose
(mg of Glucose per 100 grams)
Bee Foods: Honey 33,900
Dietary Sources of Galactose
(mg of Substance per 100 grams)
Kiwi Fruit 700
Brussels Sprouts 4,100
Beans – Green 4,100
Peas – Green 800
Dietary Sources of Fucose:
Fucoidan containing plants including several species of
seaweed such as Kelp and Wakame.
Dietary Sources of N-acetylneuraminic acid or sialic acid:
Whey protein isolate.
Dietary Sources of N-acetylglucosamine:
Shiitake Mushroom (as a constituent of chitin).
Dietary Sources of N-acetyl-galactosamine:
A red algae called Dumontiaceae (as a constituent of dextran
I think there is still some debate about whether the term "essential" is
correct. This is because they can be manufactured from the main sugar,
glucose, in the human body, though the ability to do this may be limited during
disease states. There may also be other sugar molecules equally as "essential".
The medicinal value of these simple sugars is not, however, in question.